Article

TIM-3 blockade enhances ex vivo stimulated allogeneic NK cell therapy for relapsed murine neuroblastoma after hematopoietic cell transplant

2024-07-12

Abstract excerpt

<h4>Background: </h4> High-risk neuroblastoma (HR-NBL) is an aggressive tumor of the sympathetic nervous system with high risk of relapse and poor overall survival. Allogeneic hematopoietic cell transplant (allo-HCT) has been used previously in HR-NBL patients; however, graft-versus-host-disease (GVHD) and disease progression have limited clinical application. Ex-vivo stimulated allogeneic natural killer (NK) cell...

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Literature Corpus work: 82e647cf-1648-5710-a3ed-bd5e8109da07
DOI: 10.1101/2024.07.09.602731

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