Article

The membrane skeleton density of red blood cells in <i>MYH9</i> -related disease patients is decreased

2025-02-15

Abstract excerpt

MYH9 -related disease ( MYH9 -RD) is a rare autosomal dominant disorder caused by mutations in MYH9 gene, which encodes the heavy chain of nonmuscle myosin IIA. Nearly all MYH9 -RD patients present with macrothrombocytopenia, characterized by decreased platelet count and increased platelet size. In this study, we collected blood samples from three MYH9 -RD patients (R702S, D1424N, and R1464C) and unexpectedly...

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Literature Corpus work: 82e45c17-19af-57a2-9655-d6e7dc9ebc84
DOI: 10.1101/2025.02.11.637639

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