Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MYH9: Structure, functions and role of non-muscle myosin IIA in human disease.

Gene - 20 Jul 2018

Pecci Alessandro, Ma Xuefei, Savoia Anna, Adelstein Robert S

Abstract excerpt

The MYH9 gene encodes the heavy chain of non-muscle myosin IIA, a widely expressed cytoplasmic myosin that participates in a variety of processes requiring the generation of intracellular chemomechanical force and translocation of the actin cytoskeleton. Non-muscle myosin IIA functions are regulated by phosphorylation of its 20 kDa light chain, of the heavy chain, and by interactions with other proteins. Variants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Deafness
Share to Hearing Loss, Sensorineural
Share to Molecular Motor Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Myosin Heavy Chains

Share to Neoplasms

Share to Phosphorylation

Share to Renal Insufficiency, Chronic

Share to Thrombocytopenia

Source

Open in PubMed Open full text

Identifiers

PMID: 29679756
DOI: 10.1016/j.gene.2018.04.048
PMCID: PMC5970098

Genes

MYH9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MYH9: Structure, functions and role of non-muscle myosin IIA in human disease.PMID 29679756Read ↗

Research Advances in the Physiological and Pathological Function of MYH9 and NMIIA.Semantic proximity Read ↗

Research progress of myosin heavy chain genes in human genetic diseases.Semantic proximity Read ↗

MYH9: A key protein involved in tumor progression and virus-related diseases.Semantic proximity Read ↗

MYH7 in cardiomyopathy and skeletal muscle myopathy.Semantic proximity Read ↗

Non-Muscle Myosin II A: Friend or Foe in Cancer?Semantic proximity Read ↗

Advances in the understanding of MYH9 disorders.Semantic proximity Read ↗

The mammalian myosin heavy chain gene family.Semantic proximity Read ↗

Linking the Landscape of MYH9-Related Diseases to the Molecular Mechanisms that Control Non-Muscle Myosin II-A Function in Cells.Semantic proximity Read ↗

Exploring the nexus between MYH9 and tumors: novel insights and new therapeutic opportunitiesSemantic proximity Read ↗

MYH9-siRNA and MYH9 mutant alleles: expression in cultured cell lines and their effects upon cell structure and function.Semantic proximity Read ↗

Genetic association of MYH genes with hereditary hearing loss in Korea.Semantic proximity Read ↗

[Gene analysis and clinical features of MYH9-related disease].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.