Article

Testis single-cell RNA-seq reveals the dynamics of <i>de novo</i> gene transcription and germline mutational bias in <i>Drosophila</i>

2019-07-02

Abstract excerpt

<h4>Summary</h4> The testis is a peculiar tissue in many respects. It shows patterns of rapid gene evolution and provides a hotspot for the origination of genetic novelties such as de novo genes, duplications and mutations. To investigate the expression patterns of genetic novelties across cell types, we performed single-cell RNA-sequencing of adult Drosophila testis. We found that new genes were expressed in v...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 82e43f71-67a9-5a03-a0c3-9638041d98d4
DOI: 10.1101/689687

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Testis single-cell RNA-seq reveals the dynamics of <i>de novo</i> gene transcription and germline mutational bias in <i>Drosophila</i>DOI 10.1101/689687Read

On the origin and evolution of <i>Drosophila</i> new genes during spermatogenesisSemantic proximity Read

Comparative single cell analysis of transcriptional bursting reveals the role of genome organization on <i>de novo</i> transcript originationSemantic proximity Read

Meiotic Sex Chromosome Inactivation: conservation across the <i>Drosophila</i> genusSemantic proximity Read

Dichotomous transcriptome divergence at the cell-type level between the <i>Drosophila</i> male and female germlinesSemantic proximity Read

Single cell RNA-seq in Drosophila testis reveals evolutionary trajectory of sex chromosome regulationSemantic proximity Read

Identifying candidate <i>de novo</i> genes expressed in the somatic female reproductive tract of <i>Drosophila melanogaster</i>Semantic proximity Read

The origin and structural evolution of <i>de novo</i> genes in <i>Drosophila</i>Semantic proximity Read

Transcriptional and mutational signatures of the aging germlineSemantic proximity Read

A single cell atlas reveals unanticipated cell type complexity in <i>Drosophila</i> ovariesSemantic proximity Read

Transcriptional and mutational signatures of the Drosophila ageing germline.Semantic proximity Read

On the regulatory evolution of new genes throughout their life historySemantic proximity Read

Polymorphism and Divergence of Novel Gene Expression Patterns in Drosophila melanogaster.Semantic proximity Read