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Article

Compartment-specific total RNA profile of Hippocampal and Cortical cells from Mesial Temporal Lobe Epilepsy tissue

2021-12-05

Abstract excerpt

Mesial temporal lobe epilepsy (mTLE) is a chronic neurological disease characterized by recurrent seizures. The pathogenic mechanisms underlying mTLE involve defects in post-transcriptional regulation of gene expression. So far, transcriptome profiles from epileptic tissue have been generated using whole cells, thereby lacking information on RNA localization and function at a subcellular level. In line with this,...

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Literature Corpus work
82df5956-b4da-5a16-86bd-3cdd5577acae
DOI
10.1101/2021.12.03.21266858
Open publication

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