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High diversity of<i>Escherichia coli</i>causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approach

2024-09-26

Abstract excerpt

Escherichia coli is an important cause of neonatal sepsis and the third most prevalent cause of neonatal infection in sub-Saharan Africa, often with negative outcomes. Development of maternally administered vaccines is under consideration, but to provide adequate protection, an understanding of serotypes causing invasive disease in this population is essential. We describe the genomic characteristics of a collecti...

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Literature Corpus work
38b97ddf-c0c9-530b-9a86-a183ddbc9410
DOI
10.1101/2024.09.24.24314145
Open publication

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High diversity of<i>Escherichia coli</i>causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approachDOI 10.1101/2024.09.24.24314145
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