Back to search

Article

Extended-Spectrum Beta-Lactamase <i>Klebsiella pneumoniae</i> on a Malawian neonatal unit is amplified by neonates and transmitted by maternal hands, cots and ward surfaces

2025-08-15

Abstract excerpt

<h4>Background</h4> Klebsiella pneumoniae ( Kpn ) is an important cause of neonatal sepsis in sub-Saharan Africa. Kpn are intrinsically resistant to penicillins and frequently resistant to gentamicin and 3 rd -generation cephalosporins, key agents in the treatment of neonatal sepsis. Such infections can be prevented by effective infection prevention and control (IPC), but the most effective IPC packages for resou...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b4b6a747-b637-5700-8521-63ef0b0fc443
DOI
10.1101/2025.08.13.25333346
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Extended-Spectrum Beta-Lactamase <i>Klebsiella pneumoniae</i> on a Malawian neonatal unit is amplified by neonates and transmitted by maternal hands, cots and ward surfacesDOI 10.1101/2025.08.13.25333346
High ward-level and within-sample diversity of <i>Klebsiella pneumoniae</i> on a Malawian neonatal unit revealed by single colony whole genome sequencing and post-enrichment metagenomicsSemantic proximity
Low birthweight neonates and those with long hospital stays are most at risk of antimicrobial-resistant <i>Klebsiella pneumoniae</i> infection in Malawi: implications for antibiotic prescribingSemantic proximity
Contribution of nosocomial transmission to <i>Klebsiella pneumoniae</i> neonatal sepsis in Africa and South Asia: analysis of infection clusters inferred from pathogen genomics and temporal dataSemantic proximity
Molecular surveillance reveals widespread colonisation by carbapenemase and extended spectrum beta-lactamase producing organisms in neonatal units in Kenya and NigeriaSemantic proximity
Transmission dynamics of <i>Klebsiella pneumoniae</i> in a neonatal intensive care unit in Zambia before and after an infection control bundleSemantic proximity
Molecular characterisation of a <i>Klebsiella pneumoniae</i> neonatal sepsis outbreak in a rural Gambian hospital: a retrospective genomic epidemiology investigationSemantic proximity
Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low- and middle-income countries.Semantic proximity
Molecular and clinical insights into extended-spectrum β-lactamase genes of Klebsiella pneumoniae isolated from neonatal sepsis in EthiopiaSemantic proximity
High diversity of<i>Escherichia coli</i>causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approachSemantic proximity
Molecular epidemiology and antimicrobial resistance phenotype of paediatric bloodstream infections caused by Gram-negative bacteria in Oxfordshire, UKSemantic proximity
Genomic characterization of<i>Klebsiella pneumoniae</i>causing invasive disease in South African infants: observational studies between 2018 to 2023Semantic proximity
Prospective whole-genome sequencing uncovers factors influencing bacterial transmission in neonates (PROtect NEO)Semantic proximity
Select a neighboring publication to make it the new centre.