Article
Exploring novel aspects of choline phospholipid metabolism in cancer using metabolomics
2015-01-01
Abstract excerpt
Abnormal metabolic phenotypes can be a powerful resource for drug and biomarker discoveries. In this thesis, a metabolomic approach was used to examine several aspects of tumour metabolism with potential clinical applications. In the first part, the metabolic consequences of PIK3CA mutation in MCF10A breast cells were assessed. PIK3CA mutation is oncogenic, and is important for disease progression in many breast t...
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Identifiers and source
- Literature Corpus work
- 8208cbf2-5a8a-5c6b-bfb7-99d466764729
- DOI
- 10.25560/32353