Article

Mechanistic study of exosomal high expression of miRNA-29b-3p promoting epithelial mesenchymal transition through hypomethylation in biliary atresia liver fibrosis

2024-05-08

Abstract excerpt

<title>Abstract</title> <p>Biliary atresia (BA) is one of the most common diseases of the hepatobiliary system in infants and children, but its etiology and associated pathogenesis remain unclear. The aim of this study was to investigate the mechanism related to the regulation of epithelial mesenchymal transition (EMT) through methylation of miRNA-29b-3p, which is highly expressed in exosomes and leads to hepatic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 81b92f90-713e-5e77-800a-649c5df32ae5
DOI: 10.21203/rs.3.rs-4297819/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mechanistic study of exosomal high expression of miRNA-29b-3p promoting epithelial mesenchymal transition through hypomethylation in biliary atresia liver fibrosisDOI 10.21203/rs.3.rs-4297819/v1Read

MiRNA-29b accelerates the PDGF in exosomes and stimulates hepatic stellate cells to promote liver fibrosis in biliary atresiaSemantic proximity Read

MicroRNA-29b/142-5p contribute to the pathogenesis of biliary atresia by regulating the IFN-γ geneSemantic proximity Read

Serum microRNA microarray analysis identifies miR-4429 and miR-4689 are potential diagnostic biomarkers for biliary atresiaSemantic proximity Read

Integrative genomics identifies candidate microRNAs for pathogenesis of experimental biliary atresiaSemantic proximity Read

MicroRNA-21/PTEN/Akt axis in the fibrogenesis of biliary atresiaSemantic proximity Read

MicroRNA Profiling Identifies miR‐29 as a Regulator of Disease‐associated Pathways in Experimental Biliary AtresiaSemantic proximity Read

Transcriptome profiling of biliary atresia from new born infants by deep sequencing.Semantic proximity Read

Downregulation of microRNA-145 may contribute to liver fibrosis in biliary atresia by targeting ADD3Semantic proximity Read

Septin 2 accelerates the progression of biliary tract cancer and is negatively regulated by mir-140-5pSemantic proximity Read

Function and Regulation of MicroRNAs and Their Potential as Biomarkers in Paediatric Liver DiseaseSemantic proximity Read

Circulating MicroRNA Is a Biomarker of Biliary AtresiaSemantic proximity Read

Recent advances in understanding biliary atresiaSemantic proximity Read