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Article

Downregulation of microRNA-145 may contribute to liver fibrosis in biliary atresia by targeting ADD3

13 Sept 2017

Abstract excerpt

BACKGROUND AND OBJECTIVES: Biliary atresia (BA) is a pediatric liver disease characterized by fibro-obliteration and obstruction of the extrahepatic biliary system, that invariably leads to cirrhosis and even death, if left untreated for extended time. However, its pathology and etiology still remained unknown. In this study, we tested the expression of adducin 3 (ADD3), the gene identified as a susceptibility...

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PMID: 28902846
DOI: 10.1371/journal.pone.0180896

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