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Article

MicroRNA Profiling Identifies miR‐29 as a Regulator of Disease‐associated Pathways in Experimental Biliary Atresia

14 Dec 2011

Abstract excerpt

Biliary atresia (BA) is a pediatric liver disease of unknown underlying etiology, in which fibroinflammatory destruction of the extrahepatic biliary system leads to obstructive cholestasis. MicroRNAs are a class of short (18-23 nucleotide), noncoding RNA molecules, which act as negative regulators of target mRNA stability and translation. The importance of these molecules in normal and diseased liver has been...

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PMID: 22167021
DOI: 10.1097/mpg.0b013e318244148b

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