Article

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity

2020-09-13

Abstract excerpt

<h4>ABSTRACT</h4> Angiotensin-converting enzyme 2 (ACE2) maintains cardiovascular and renal homeostasis but also serves as the entry receptor for the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), the causal agent of novel coronavirus disease 2019 (COVID-19) 1 . COVID-19 disease severity, while highly variable, is typically lower in pediatric patients than adults (particularly the elderly), bu...

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Literature Corpus work: 81a32526-9548-5f84-85a5-45f3fe1ef8a7
DOI: 10.1101/2020.09.13.276923

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