Article

EPIGENETIC AGE ACCELERATION, LUNG FUNCTION AND COPD ACROSS THE LIFESPAN

2025-10-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Chronic Obstructive Pulmonary Disease (COPD) is considered an aging-associated disease but can have its origin early in life. Chronological age is an imprecise measure of biological aging. To accurately measure biological age and age acceleration, different generations of epigenetic clocks have been developed. <h4>Objective</h4> To evaluate the role of epigenetic age acceler...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8180e85f-e981-5eac-87b8-8b9eda4faf5c
DOI: 10.1101/2025.10.27.25338710

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

EPIGENETIC AGE ACCELERATION, LUNG FUNCTION AND COPD ACROSS THE LIFESPANDOI 10.1101/2025.10.27.25338710Read

Accelerated epigenetic aging as a risk factor for chronic obstructive pulmonary disease and decreased lung function in two prospective cohort studies.Semantic proximity Read

DNA Methylation-Based Age Prediction and Telomere Length Reveal an Accelerated Aging in Induced Sputum Cells Compared to Blood Leukocytes: A Pilot Study in COPD PatientsSemantic proximity Read

Association between phenotypic age acceleration and mortality in patients with chronic obstructive pulmonary disease.Semantic proximity Read

Epigenetic age acceleration in idiopathic pulmonary fibrosis revealed by DNA methylation clocksSemantic proximity Read

Effect of tobacco smoking on the epigenetic age of human respiratory organsSemantic proximity Read

Accelerated lung aging and chronic obstructive pulmonary diseaseSemantic proximity Read

Accelerated epigenetic age, inflammation, and gene expression in lung: comparisons of smokers and vapers with non-smokersSemantic proximity Read

Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burdenSemantic proximity Read

The evolving epidemiology, disease trajectories and etiotypes of COPD.Semantic proximity Read

Examining the Effects of Age on Health Outcomes of Chronic Obstructive Pulmonary Disease: Results From the Genetic Epidemiology of Chronic Obstructive Pulmonary Disease Study and Evaluation of Chronic Obstructive Pulmonary Disease Longitudinally to Identify Predictive Surrogate Endpoints Cohorts.Semantic proximity Read

Epigenetic age and lung cancer risk in the CLUE II prospective cohort studySemantic proximity Read

Lung ageing and COPD: is there a role for ageing in abnormal tissue repair?Semantic proximity Read