Article
Association between phenotypic age acceleration and mortality in patients with chronic obstructive pulmonary disease.
Respiratory medicine - 1 Jan 2026
Cheng Huijuan, Lin Cuili, Chen Shun, Lin Weilan, Lu Feng
Abstract excerpt
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide. Chronological age poorly reflects biological heterogeneity in prognosis. Phenotypic age acceleration (PhenoAgeAccel), a biomarker of multisystem biological aging, may offer prognostic value beyond traditional risk factors. OBJECTIVES: We investigated whether PhenoAgeAccel predicts all-cause and cause-specific...
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