Article
Accelerated epigenetic aging as a risk factor for chronic obstructive pulmonary disease and decreased lung function in two prospective cohort studies.
Aging - 3 Aug 2020
Breen Miyuki, Nwanaji-Enwerem Jamaji C, Karrasch Stefan, Flexeder Claudia, Schulz Holger, Waldenberger Melanie, Kunze Sonja, Ollert Markus, Weidinger Stefan, Colicino Elena, Gao Xu, Wang Cuicui, Shen Jincheng, Just Allan C, Vokonas Pantel, Sparrow David, Hou Lifang, Schwartz Joel D, Baccarelli Andrea A, Peters Annette, Ward-Caviness Cavin K
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is a frequent diagnosis in older individuals and contributor to global morbidity and mortality. Given the link between lung disease and aging, we need to understand how molecular indicators of aging relate to lung function and disease. Using data from the population-based KORA (Cooperative Health Research in the Region of Augsburg) surveys, we associated baseline...
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