Identification of Immune-Related Key Genes as Potential Diagnostic Biomarkers of Sepsis in Children

Abstract excerpt

Objective: The pathogenesis of sepsis is still unclear due to its complexity, especially in children. This study aimed to analyse the immune microenvironment and regulatory networks related to sepsis in children at the molecular level and to identify key immune-related genes to provide a new basis for the early diagnosis of sepsis. Methods: The GSE145227 and GSE26440 datasets were downloaded from the Gene...