Article

Paternal-age-related de novo mutations and risk for five disorders

2017-09-22

Abstract excerpt

<h4>Background</h4> There are well-established epidemiologic associations between advanced paternal age and increased offspring risk for several psychiatric and developmental disorders. These associations are commonly attributed to age-related de novo mutations. However, the actual magnitude of risk conferred by age-related de novo mutations in the male germline is unknown. Quantifying this risk would clarify t...

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Literature Corpus work: 80ed0b4b-cc8e-51ab-b27f-de3bec95159e
DOI: 10.1101/192740

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