Article

Required concentration index quantifies effective drug combinations against hepatitis C virus infection

2020-12-09

Abstract excerpt

Successful clinical drug development requires rational design of combination treatments based on preclinical data. Anti-HCV drugs exhibit significant diversity in antiviral effect. Dose-response assessments can be used to determine parameters profiling the diverse antiviral effect during combination treatment. In the current study, a combined experimental and mathematical approaches were used to compare and score...

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Literature Corpus work: 80b528e1-466d-59ef-bcd1-a6ff302f92ff
DOI: 10.21203/rs.3.rs-34401/v2

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