Article

Role of endothelial microRNA-150 in pulmonary arterial hypertension

2020-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Endothelial dysfunction contributes to the vascular pathology in pulmonary arterial hypertension (PAH). Circulating levels of endothelial miR-150 are reduced in PAH and act as an independent predictor of patient survival. The role of endothelial miR-150 in vascular dysfunction in PAH is not well understood. Endothelium-targeted miR-150 delivery prevented the disease in Sugen/hypoxia mice, while...

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Literature Corpus work: 212cf572-64bc-5418-98f0-a7bbcffe5130
DOI: 10.1101/2020.03.25.007021

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