Hidden Viral Footprints: Genome-Wide Screening of Candidate Viral-like Loci in the Human GRCh38.p14 Genome

Abstract excerpt

<title>Abstract</title> <p>This study performed a large-scale computational genomic screen to identify candidate viral-like loci within the human GRCh38.p14 genome by aligning a viral reference database against segmented human genomic references. Viral sequences were aligned using minimap2, and candidate loci were retained using MAPQ > = 20, alignment length > = 100 bp, and sequence identity > = 80%. After duplic...

Topics

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• Endogenous Retroviruses
• Gene Expression
• Gene Products, gag
• Genes, Viral
• Open Reading Frames
• Proviruses
• Sequence Alignment
• Terminal Repeat Sequences

Identifiers and source

Literature Corpus work

806834b1-cc49-5465-a9d5-3b936ad731ad

DOI

10.21203/rs.3.rs-9602284/v1