Article
Sequence variability, gene structure, and expression of full-length human endogenous retrovirus H.
Journal of virology - 1 May 2005
Jern Patric, Sperber Göran O, Ahlsén Göran, Blomberg Jonas
Abstract excerpt
Recently, we identified and classified 926 human endogenous retrovirus H (HERV-H)-like proviruses in the human genome. In this paper, we used the information to, in silico, reconstruct a putative ancestral HERV-H. A calculated consensus sequence was nearly open in all genes. A few manual adjustments resulted in a putative 9-kb HERV-H provirus with open reading frames (ORFs) in gag, pro, pol, and env. Long...
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