Article

Spike-specific CXCR3 <sup>+</sup> T <sub>FH</sub> cells play a dominant functional role in supporting antibody responses in SARS-CoV-2 infection and vaccination

2022-08-09

Abstract excerpt

<h4>Summary</h4> CD4 + T follicular helper (T FH ) cells are required for high-quality antibody generation and maintenance. However, the longevity and functional role of these cells are poorly defined in COVID-19 convalescents and vaccine recipients. Here, we longitudinally investigated the dynamics and functional roles of spike-specific circulating T FH cells and their subsets in convalescents at the 2 nd ,...

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Literature Corpus work: 7f7c724a-2612-5420-859f-b2ff256956d9
DOI: 10.1101/2022.08.09.503302

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