Article

Impact of Highly Effective CFTR Modulator Therapy on Physical Activity, Sleep, and Sinonasal Symptoms in Preschool Children with Cystic Fibrosis: A Prospective Single-Center Pilot Study

2026-05-06

Abstract excerpt

<h4>Background: </h4> Highly effective CFTR modulation with Elexacaftor/Tezacaftor/Ivacaftor (ETI) markedly improves clinical outcomes in people with cystic fibrosis (CF). Data on its effects on physical activity, sleep, sinonasal symptoms and parent-perceived outcomes in preschool-aged children are limited. <h4>Methods:</h4> In this prospective, observational, single-center cohort study, ten children with cystic...

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Literature Corpus work: 7f2f9349-ec52-56f2-a9f1-32db2de074bc
DOI: 10.20944/preprints202605.0319.v1

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