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Article

Elexacaftor-Tezacaftor-Ivacaftor improves exercise capacity in adolescents with cystic fibrosis.

Pediatric pulmonology - 1 Nov 2022

Causer Adam J, Shute Janis K, Cummings Michael H, Shepherd Anthony I, Wallbanks Samuel R, Pulsford Richard M, Bright Victoria, Connett Gary, Saynor Zoe L

Abstract excerpt

OBJECTIVE: Elexacaftor/Tezacaftor/Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator with the potential to improve exercise capacity. This case series of three adolescents with CF aimed to investigate whether 6 weeks treatment with Elexacaftor/Tezacaftor/Ivacaftor could improve exercise capacity in CFTR modulator naive adolescents with CF. METHODS: Three adolescents (14.0 ± 1.4...

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Identifiers

PMID: 35851858
DOI: 10.1002/ppul.26078
PMCID: PMC9795914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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