Article
Effect of highly effective modulator therapy on quality of life in adults with cystic fibrosis.
International forum of allergy & rhinology - 1 Jan 2021
DiMango Emily, Spielman Daniel B, Overdevest Jonathan, Keating Claire, Francis Sarah Fracasso, Dansky David, Gudis David A
Abstract excerpt
BACKGROUND: Elexacaftor/tezacaftor/ivacaftor is a highly effective modulator that improves function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, resulting in improved pulmonary function in patients with cystic fibrosis (CF). We hypothesize that improvements in lung function are associated with improvements in health-related quality of life and sinonasal health. The aim of this study...
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