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The mechanism by which ADAM10 cleaves Notch2 and upregulates RAB5 to regulate exosome secretion in pancreatic cancer

2023-07-17

Abstract excerpt

<h4>Background: </h4> At present, the clinical diagnosis and treatment of pancreatic cancer (PC) are challenging, and there are still in gaps in the knowledge about its malignant progression. In particular, there is not enough information about the mechanism by which exosomes released by PC cells are significantly increased and involved in promoting malignant progression. Results In the present study, the express...

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Literature Corpus work
7f191841-a77c-54e7-b1a9-c529feb9ed92
DOI
10.21203/rs.3.rs-3158671/v1
Open publication

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The mechanism by which ADAM10 cleaves Notch2 and upregulates RAB5 to regulate exosome secretion in pancreatic cancerDOI 10.21203/rs.3.rs-3158671/v1
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