Article

MOLECULAR CORRELATE OF MOUSE EXECUTIVE FUNCTION. TOP-DOWN AND BOTTOM-UP COMPLEMENTATIONS BY PRESYNAPTIC VERTEBRATE BRAIN-SPECIFIC Ntng GENE PARALOGS

2017-05-18

Abstract excerpt

<h4>ABSTRACT</h4> Executive function (EF) is a regulatory construct of learning and general cognitive abilities. Genetic variations underlying the architecture of cognitive phenotypes are likely to affect EF and associated behaviors. Mice lacking one of Ntng gene paralogs, encoding the vertebrate brain-specific presynaptic Netrin-G proteins, exhibit prominent deficits in the EF control. Brain areas responsible f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7efb7012-2151-5370-bf79-36db0d03c593
DOI: 10.1101/139444

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MOLECULAR CORRELATE OF MOUSE EXECUTIVE FUNCTION. TOP-DOWN AND BOTTOM-UP COMPLEMENTATIONS BY PRESYNAPTIC VERTEBRATE BRAIN-SPECIFIC Ntng GENE PARALOGSDOI 10.1101/139444Read

Synaptic scaffold evolution generated components of vertebrate cognitive complexity.Semantic proximity Read

Diversification of behavior and postsynaptic properties by netrin-G presynaptic adhesion family proteins.Semantic proximity Read

AI-based decoding of long covid cognitive impairments in mice using automated behavioral system and comparative transcriptomic analysisSemantic proximity Read

Uncovering the Genetic Profiles Underlying the Intrinsic Organization of the Human CerebellumSemantic proximity Read

GWAS-based pathway analysis differentiates between fluid and crystallized intelligence.Semantic proximity Read

Behavioral Testing Design for Evaluation of Cognitive Disabilities.Semantic proximity Read

Genetic association between posterior parietal cortex and intelligenceSemantic proximity Read

Cognitive Endophenotypes of Modern and Extinct Hominins Associated with <i>NTNG</i> Gene ParalogsSemantic proximity Read

Genetic landscape of adult executive function reveals a cell-type-specific developmental origin.Semantic proximity Read

Large and fast excitatory transcriptomic neuron types in human cortex preferentially express genes of intelligence and HARs.Semantic proximity Read

Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in male 3xTg Alzheimer’s model miceSemantic proximity Read

Depletion of neurocan in the prefrontal cortex impairs temporal order recognition, cognitive flexibility and perisomatic GABAergic innervationSemantic proximity Read