Article
Genetic landscape of adult executive function reveals a cell-type-specific developmental origin.
Nature communications - 2 May 2026
Rahman Md Shafiqur, Frkatović-Hodžić Azra, van den Ameele Jelle, Hill Steven M, Kingston Nathalie, Bradley John R, Tom Brian D M, Chinnery Patrick F
Abstract excerpt
Executive function is an essential cognitive domain for typical human behavior which is disrupted in neurodevelopmental and neurodegenerative disorders, but little is known about its underlying molecular basis. To address this, we perform genome-wide association studies (GWAS) using three different measures of executive function in UK Biobank (N = 84,238) and NIHR BioResource's Genes and Cognition (N = 9932)...
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