Article

Deletion detection in SARS-CoV-2 genomes using multiplex-PCR sequencing from COVID-19 patients: elimination of false positives

2025-04-16

Abstract excerpt

Deletions are prevalent in the genomes of SARS-CoV-2 isolates from COVID-19 patients, but their roles in the severity, transmission, and persistence of disease are poorly understood. Millions of COVID-19 swab samples from patients have been sequenced and made available online, offering an unprecedented opportunity to study such deletions. Multiplex PCR-based amplicon sequencing (amplicon-seq) has been the most wid...

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Literature Corpus work: 7ea53a8c-9654-5946-9d93-6fce00fd7bb2
DOI: 10.1101/2025.04.15.25325794

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