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Article

Development and validation of a high throughput SARS-CoV-2 whole genome sequencing workflow in a clinical laboratory.

Scientific reports - 8 Feb 2022

Rosenthal Sun Hee, Gerasimova Anna, Ruiz-Vega Rolando, Livingston Kayla, Kagan Ron M, Liu Yan, Anderson Ben, Owen Renius, Bernstein Laurence, Smolgovsky Alla, Xu Dong, Chen Rebecca, Grupe Andrew, Tanpaiboon Pranoot, Lacbawan Felicitas

Abstract excerpt

Monitoring new mutations in SARS-CoV-2 provides crucial information for identifying diagnostic and therapeutic targets and important insights to achieve a more effective COVID-19 control strategy. Next generation sequencing (NGS) technologies have been widely used for whole genome sequencing (WGS) of SARS-CoV-2. While various NGS methods have been reported, one chief limitation has been the complexity of the...

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Identifiers

PMID: 35136154
DOI: 10.1038/s41598-022-06091-0
PMCID: PMC8826425

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