Article

Pan-Cancer transcriptomics reveals diverse R-loop events based on multiple machine learning algorithms

2023-12-28

Abstract excerpt

<h4>Background: </h4> R-loops are three-stranded RNA-DNA hybrids which play an important role in various cellular and chromosomal function including transcriptional regulation and genome instability. Due to the absence of approach characterizing R-Loops events at a larger scale, we developed a computational metrics as R-Loops score to decipher the landscape of R-Loops events at a pan-cancer level and within LUAD p...

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Literature Corpus work: 7e73472a-1512-5f03-9ff7-3ff5bc18fe76
DOI: 10.21203/rs.3.rs-3785133/v1

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