Article

Imaging Mass Cytometry (IMC) as a Tool to Characterize Circulating Tumor Cells (CTCs) in Preclinical Mouse Models

2025-12-22

Abstract excerpt

Circulating tumor cells (CTCs), particularly multicellular clusters, are associated with poor prognosis and may provide insight into mechanisms of metastasis and therapy resistance. Unbiased approaches for functionally characterizing CTCs in liquid biopsies are therefore urgently needed. Here, we evaluate multiplex imaging mass cytometry (IMC) for CTC analysis in mice bearing human xenograft tumors. In a single-st...

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Literature Corpus work: 7e1f3491-0abb-57c0-9cf2-426d79c81b07
DOI: 10.64898/2025.12.18.695262

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