Article

PRESCOTT: a population aware, epistatic and structural model accurately predicts missense effect

2024-02-06

Abstract excerpt

Predicting the functional impact of point mutations is a complex yet vital task in genomics. PRESCOTT stands at the forefront of this challenge and reconstructs complete mutational landscapes of proteins, enables the identification of protein regions most vulnerable to mutations and assigns scores to individual mutations, assisting pathologists in evaluating the pathogenic potential of missense variants. PRESCOTT...

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Literature Corpus work: 7de0a0f6-ee6f-5a07-bbaa-7acbe7e82497
DOI: 10.1101/2024.02.03.24302219

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