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Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of <i>Borrelia burgdorferi</i> Elp Proteins

2024-08-24

Abstract excerpt

Lyme disease is a tick-borne spirochetosis with diverse clinical manifestations. Phenotypic variation among Borrelia burgdorferi strains correlates with variable manifestations of Lyme disease in humans; this diversity is attributed in part to variation in surface-exposed lipoproteins, which are targets of the human antibody response and contribute to tissue adhesion, immune evasion, and other host interactions....

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Literature Corpus work
7dd1f8b0-00a4-507f-b593-4d40adb3a2c3
DOI
10.1101/2024.08.23.609448
Open publication

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Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of <i>Borrelia burgdorferi</i> Elp ProteinsDOI 10.1101/2024.08.23.609448
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