Article

Single-cell transcriptomic atlas reveals increased regeneration in diseased human inner ears

2022-10-31

Abstract excerpt

Mammalian inner ear hair cell loss leads to permanent hearing and balance dysfunction. In contrast to the cochlea, vestibular hair cells of the murine utricle have some regenerative capacity. Whether human utricular hair cells regenerate remains unknown. Here we procured live, mature utricles from organ donors and vestibular schwannoma patients, and present a validated single-cell transcriptomic atlas at unprecede...

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Literature Corpus work: 7da29765-8e87-5beb-b649-c531ebfea336
DOI: 10.1101/2022.10.29.514378

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