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Ribosomal DNA methylation as stable biomarkers for detection of cancer in plasma

2019-05-29

Abstract excerpt

<h4>Background</h4> Recently, liquid biopsy for cancer detection has pursued great progress. However, there are still a lack of high quality markers. It is a challenge to detect cancer stably and accurately in plasma cell free DNA (cfDNA), when the ratio of cancer signal is low. Repetitive genes or elements may improve the robustness of signals. In this study, we focused on ribosomal DNA which repeats hundreds of...

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Literature Corpus work
7d94c739-2ab3-585b-bda0-af230ff59f12
DOI
10.1101/651497
Open publication

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