Article

Drug Resistance Mutations in the Polymerase Gene of HBV in Three Generations of Patients with Chronic Hepatitis B

2025-09-30

Abstract excerpt

<title>Abstract</title> <p> Hepatitis B virus polymerase proofreading defects lead to frequent DNA mutations in the hepatitis B virus genome and contribute to treatment resistance. This study aimed to examine drug-resistant mutations in three generations of patients with chronic hepatitis B. <bold/> Based on the inclusion criteria, 90 chronic HBV patients in northeastern Iran were divided into three groups. HB...

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Literature Corpus work: 4f14a969-b6b1-58b6-a6dc-f83121fcde95
DOI: 10.21203/rs.3.rs-7394867/v1

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