Article

TAC-seq: targeted DNA and RNA sequencing for precise biomarker molecule counting

2018-04-05

Abstract excerpt

Targeted next-generation sequencing based biomarker detection methods have become essential for biomedical diagnostics. In addition to their sensitivity and high-throughput capacity, absolute molecule counting based on unique molecular identifier (UMI) has high potential to increase biomarker detection accuracy even further through the reduction of systematic technical biases. Here, we present TAC-seq, a simple an...

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Literature Corpus work: 7ce14dcb-60d4-5ff0-8dc4-fc150ab83925
DOI: 10.1101/295253

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