Article

Comprehensive genome sequencing analysis as a promising option in the prenatal diagnosis of fetal structural anomalies: a prospective study

2020-08-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Genome sequencing (GS) is a powerful tool for postnatal genetic diagnosis, but relevant clinical studies in the field of prenatal diagnosis are few. We aimed to evaluate the feasibility of GS as a first-line approach in prenatal diagnosis and compare its clinical value with the chromosomal microarray analysis (CMA) plus exome sequencing (ES) sequential testing. <h4>Methods</h4>...

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Literature Corpus work: 01b8edf2-c214-506d-8760-464a0468f428
DOI: 10.1101/2020.08.22.260893

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