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Transcriptomic and proteomic analysis of quiescent epimastigotes as a resource for investigating <i>Trypanosoma cruzi</i> persistence

2025-09-09

Abstract excerpt

Chagas disease is caused by infection with the protozoan parasite Trypanosoma cruzi. Despite triggering a strong immune response, infections are typically life-long and can result in severe cardiac and/or digestive tract pathology. Current drugs have limited efficacy, and treatment failure is a common outcome. Eliminating a non-replicating T. cruzi sub-population that can persist after therapy has been a key cha...

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Literature Corpus work
7ccbcfc3-a76b-5292-9fec-201b8b648199
DOI
10.1101/2025.09.09.675056
Open publication

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