Article
Exon array analysis reveals genetic heterogeneity in atypical femoral fractures. A pilot study.
Molecular and cellular biochemistry - 1 Nov 2015
Pérez-Núñez Isabel, Pérez-Castrillón José L, Zarrabeitia María T, García-Ibarbia Carmen, Martínez-Calvo Laura, Olmos José M, Briongos Laisa S, Riancho Javier, Camarero Victoria, Muñoz Vives Josep M, Cruz Raquel, Riancho José A
Abstract excerpt
Atraumatic subtrochanteric and diaphyseal (atypical) femoral fractures are a rare, but important adverse event in patients treated with potent anti-resortive agents. The mechanisms involved are unknown and particularly the association with genetic variants has not been explored. The aim of the study was to identify rare genetic variants that could be associated with the occurrence of these fractures. We performed...
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