Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Genetics of Atypical Femur Fractures-a Systematic Review.

Current osteoporosis reports - 1 Apr 2021

Zhou Wei, van Rooij Jeroen G J, Ebeling Peter R, Verkerk Annemieke J M H, Zillikens M Carola

Abstract excerpt

PURPOSE OF REVIEW: Atypical femur fractures (AFFs) are rare subtrochanteric or diaphyseal fractures regarded as side effects of bisphosphonates (BPs), possibly with a genetic background. Here, we summarize the most recent knowledge about genetics of AFFs. RECENT FINDINGS: AFF has been reported in 57 patients with seven different monogenic bone disorders including hypophosphatasia and osteogenesis imperfecta;...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Density Conservation Agents
Share to Bone Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Farnesyltranstransferase

Share to Genome-Wide Association Study

Share to Membrane Transport Proteins

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 33587247
DOI: 10.1007/s11914-021-00658-y
PMCID: PMC8016774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Genetics of Atypical Femur Fractures-a Systematic Review.PMID 33587247Read ↗

Prevalence of Monogenic Bone Disorders in a Dutch Cohort of Atypical Femur Fracture PatientsSemantic proximity Read ↗

Assessing the contribution of genes involved in monogenic bone disorders to the etiology of atypical femoral fracturesSemantic proximity Read ↗

Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone-Relevant Cell Types.Semantic proximity Read ↗

Assessing the contribution of genes involved in monogenic bone disorders to the etiology of atypical femoral fractures.Semantic proximity Read ↗

Current Understanding of Epidemiology, Pathophysiology, and Management of Atypical Femur Fractures.Semantic proximity Read ↗

GGPS1 Mutation and Atypical Femoral Fractures with Bisphosphonates.Semantic proximity Read ↗

Identification of a p.Arg708Gln variant in COL1A2 in atypical femoral fractures.Semantic proximity Read ↗

Identification of rare genetic variants in familial forms and unrelated cases of bisphosphonates-associated atypical femur fracture.Semantic proximity Read ↗

The Contribution of Deleterious Rare Alleles in ENPP1 and Osteomalacia Causative Genes to Atypical Femoral Fracture.Semantic proximity Read ↗

Atypical femoral fracture in a 51-year-old woman: Revealing a hypophosphatasia.Semantic proximity Read ↗

A Genome-Wide Association Study of Bisphosphonate-Associated Atypical Femoral FractureSemantic proximity Read ↗

Gene-based association analysis of a large patient cohort provides insights into genetics of atypical femur fractures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.