Article

A Negative Feedback Loop Between TET2 and Leptin in Adipocyte Regulates Body Weight

2023-09-07

Abstract excerpt

<title>Abstract</title> <p>Ten-eleven translocation (TET) 2 is an enzyme that catalyzes DNA demethylation to regulate gene expression by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine, functioning as an essential epigenetic regulator in various biological processes. However, the regulation and function of TET2 in adipocytes during obesity are poorly understood. In this study, we demonstrate that leptin, a...

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Literature Corpus work: 7c73ec06-6760-5550-947c-99c5e311b592
DOI: 10.21203/rs.3.rs-3192972/v1

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A Negative Feedback Loop Between TET2 and Leptin in Adipocyte Regulates Body WeightDOI 10.21203/rs.3.rs-3192972/v1Read

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