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Article

Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta

7 Feb 2019

Abstract excerpt

BACKGROUND: It is well established that obesity is associated with dysregulation of the ratio between the two major adipokines leptin and adiponectin. Furthermore, it was recently reported that maternal obesity has a significant impact on placental development. Leptin and adiponectin are present at the fetal-maternal interface and are involved in the development of a functional placenta. However, less is known...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 30732639
DOI: 10.1186/s13148-019-0612-6

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