Article

mTOR and epileptogenesis in developmental brain malformations

2010-12-01

Abstract excerpt

Summary Tuberous sclerosis complex and related malformations of cortical development represent common developmental causes of intractable epilepsy. Abnormalities in the mammalian target of rapamycin pathway may be central to the pathophysiology of epilepsy and other neurologic deficits in these disorders and serve as a rational target for antiepileptogenic or disease‐modifying therapies. For an expanded treatment...

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Literature Corpus work: 7c704c25-0c05-5e69-a73f-97d7e4a6a2c0
DOI: 10.1111/j.1528-1167.2010.02858.x

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