Article

Profiling Bile Acids in the Stools of Humans and Animal Models of Cystic Fibrosis

2025-05-09

Abstract excerpt

<h4>ABSTRACT</h4> Cystic fibrosis (CF) is associated with dysbiosis of the gut microbiome, alterations in intestinal mucus production, aberrant bile acid (BA) metabolism, fat malabsorption, and chronic inflammation. As little is known about BAs in CF, we performed both comprehensive and targeted BA profiling in stool of children with or without CF. Our results reveal that select BA species and metabolites are sig...

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Literature Corpus work: 7c575a0d-d06b-5533-a3ca-ab30647d3b65
DOI: 10.1101/2025.05.08.651222

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