Article

Intestinal dysbiosis and inflammation in cystic fibrosis impacts gut and multi-organ axes

2022-06-15

Abstract excerpt

Cystic fibrosis (CF) is a multisystem genetic disease which affects numerous organs in the body. Patients with CF exhibit profound alterations in the gastrointestinal microbiome, characterised by an increase in pathogenic bacteria and reduction in beneficial commensal species, accompanied by intestinal inflammation. The proposed pathophysiology of these gastrointestinal changes is multifactorial, driven primarily...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 68dbc419-c897-5d15-aadd-d873cca12fa5
DOI: 10.1016/j.medmic.2022.100057

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Intestinal dysbiosis and inflammation in cystic fibrosis impacts gut and multi-organ axesDOI 10.1016/j.medmic.2022.100057Read

Cystic fibrosis and inflammatory bowel disease: parallels in gut physiology and microbiotaSemantic proximity Read

The Intestinal Microbiome and Cystic Fibrosis Transmembrane Conductance Regulator Modulators: Emerging Themes in the Management of Gastrointestinal Manifestations of Cystic Fibrosis.Semantic proximity Read

Changing paradigms in the treatment of gastrointestinal complications of cystic fibrosis in the era of cystic fibrosis transmembrane conductance regulator modulators.Semantic proximity Read

Diet and the gut-lung axis in cystic fibrosis – direct & indirect linksSemantic proximity Read

Gastrointestinal pathophysiology and nutrition in cystic fibrosis.Semantic proximity Read

Beyond Bacteria and Fungi: Cystic Fibrosis and Possible Association with Intestinal Parasitic DiseasesSemantic proximity Read

Gut microbiome and metabolites: The potential key roles in pulmonary fibrosisSemantic proximity Read

Unraveling the gut-Lung axis: Exploring complex mechanisms in disease interplaySemantic proximity Read

The Gut Microbiota and Respiratory Diseases: New Evidence.Semantic proximity Read

Metagenomic evidence for taxonomic dysbiosis and functional imbalance in the gastrointestinal tracts of children with cystic fibrosisSemantic proximity Read

Modulation, microbiota and inflammation in the adult CF gut: A prospective study.Semantic proximity Read

The emerging roles of microbiome and short-chain fatty acids in the pathogenesis of bronchopulmonary dysplasiaSemantic proximity Read