Back to search

Article

Immune profiling, microbiome, metabolomics, and gut physiology of a 1-year controlled human hookworm infection

2023-03-20

Abstract excerpt

<title>Abstract</title> <p>The observation that experimental helminth infection can be associated with immunomodulation and suppression of inflammatory diseases at distal tissue sites, has been used as rationale for trialing helminths such as Necator americanus for the treatment of inflammatory disorders in humans. However, the lack of sufficient knowledge of the immunological interplay between human host and par...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7c0878fd-1cc7-5171-9e91-16c5f000bd6c
DOI
10.21203/rs.3.rs-2641205/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Immune profiling, microbiome, metabolomics, and gut physiology of a 1-year controlled human hookworm infectionDOI 10.21203/rs.3.rs-2641205/v1
Immune profiling, microbiome, metabolomics, and gut physiology of a 1-year controlled human hookworm infectionSemantic proximity
Controlled infection with cryopreserved human hookworm induces CTLA-4 expression on Tregs and upregulates tryptophan metabolismSemantic proximity
Exploring the impact of gastrointestinal parasitic helminths on the human microbiome using advanced biomolecular and bioinformatics technologiesSemantic proximity
Coevolutionary interplay: Helminths-trained immunity and its impact on the rise of inflammatory diseasesSemantic proximity
Natural strongyle infection reduces relative abundance of inflammation-inducing <i>Prevotella</i> in wild primatesSemantic proximity
Effects of Schistosoma haematobium infection and treatment on the systemic and mucosal immune phenotype, gene expression and microbiome: A systematic review.Semantic proximity
Diet‐microbiota crosstalk and immunity to helminth infectionSemantic proximity
High Schistosoma mansoni infection intensity is associated with distinct gut microbiome and low levels of systemic cytokines in children along the Albert-Nile, Northern UgandaSemantic proximity
Spatially-divergent metabolic impact of experimental toxoplasmosis: immunological and microbial correlatesSemantic proximity
Behavioral Cooperation or Conflict of Human Intestinal Roundworms and Microbiomes: A Bio-Activity PerspectiveSemantic proximity
Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host’s immune systemSemantic proximity
Uncovering the role of the gut microbiome and metabolome in Schistosoma mansoni-induced modulation of cardiovascular disease risk in humansSemantic proximity
Select a neighboring publication to make it the new centre.