Article
Effects of Schistosoma haematobium infection and treatment on the systemic and mucosal immune phenotype, gene expression and microbiome: A systematic review.
PLoS neglected tropical diseases - 1 Sept 2024
Mertelsmann Anna M, Bowers Sheridan F, Wright Drew, Maganga Jane K, Mazigo Humphrey D, Ndhlovu Lishomwa C, Changalucha John M, Downs Jennifer A
Abstract excerpt
BACKGROUND: Urogenital schistosomiasis caused by Schistosoma haematobium affects approximately 110 million people globally, with the majority of cases in low- and middle-income countries. Schistosome infections have been shown to impact the host immune system, gene expression, and microbiome composition. Studies have demonstrated variations in pathology between schistosome subspecies. In the case of S....
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