Article

The genomic signature of resistance to platinum-containing neoadjuvant therapy based on single-cell data

2023-03-24

Abstract excerpt

<h4>Background: </h4> Neoadjuvant chemotherapy (NACT) becomes the first-line option for advanced tumors, while patients who are not sensitive to it may not benefit. Therefore, it is important to screen patients suitable for NACT. <h4>Methods: </h4> Single-cell data of lung adenocarcinoma (LUAD) and esophageal squamous carcinoma (ESCC) before and after cisplatin-containing (CDDP) NACT and cisplatin IC50 data of tu...

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Literature Corpus work: 7bde1d02-f00f-5dbe-bb31-27ac937cef57
DOI: 10.21203/rs.3.rs-2686396/v1

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